New research has provided more evidence for connections between asthma and sex hormones. The research, funded by a grant from the National Heart, Lung, and Blood Institute for Dr Joe Zein staff in the Respiratory Institute at Cleveland Clinic, US, shows that oral contraceptive use and endometriosis are associated with a higher risk of lifetime asthma in women of reproductive age.
The team studied data on 3,272,020 women aged between 20 and 40 years of age from a national database, and found that that asthma was more prevalent in women with endometriosis (23.8 per cent compared with 13.2 per cent) across weight groups and categories. They then replicated these results using the National Health and Nutrition Examination Survey. “Our epidemiological studies continue to support a link between sex, sex hormones and asthma,” said Dr Zein. “This finding is further confirmation of our efforts to pinpoint the linking mechanisms so that we can one day develop appropriate treatments.”